2dfj

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[[Image:2dfj.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of the Diadenosine Tetraphosphate Hydrolase from Shigella flexneri 2a==
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|PDB= 2dfj |SIZE=350|CAPTION= <scene name='initialview01'>2dfj</scene>, resolution 2.72&Aring;
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<StructureSection load='2dfj' size='340' side='right'caption='[[2dfj]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>
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<table><tr><td colspan='2'>[[2dfj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri_2a Shigella flexneri 2a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFJ FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Bis(5'-nucleosyl)-tetraphosphatase_(symmetrical) Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.41 3.6.1.41] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.72&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfj OCA], [https://pdbe.org/2dfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfj RCSB], [https://www.ebi.ac.uk/pdbsum/2dfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfj ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfj OCA], [http://www.ebi.ac.uk/pdbsum/2dfj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dfj RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/APAH_SHIFL APAH_SHIFL] Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.[HAMAP-Rule:MF_00199]
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== Evolutionary Conservation ==
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'''Crystal Structure of the Diadenosine Tetraphosphate Hydrolase from Shigella flexneri 2a'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfj_consurf.spt"</scriptWhenChecked>
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2DFJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri_2a Shigella flexneri 2a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFJ OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of the diadenosine tetraphosphate hydrolase from Shigella flexneri 2a., Wang QH, Hu WX, Gao W, Bi RC, Proteins. 2006 Dec 1;65(4):1032-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17006950 17006950]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dfj ConSurf].
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[[Category: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)]]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Shigella flexneri 2a]]
[[Category: Shigella flexneri 2a]]
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[[Category: Single protein]]
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[[Category: Bi RC]]
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[[Category: Bi, R C.]]
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[[Category: Hu WX]]
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[[Category: Hu, W X.]]
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[[Category: Wang QH]]
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[[Category: Wang, Q H.]]
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[[Category: helices and strands mixture]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:34:02 2008''
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Current revision

Crystal Structure of the Diadenosine Tetraphosphate Hydrolase from Shigella flexneri 2a

PDB ID 2dfj

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