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1jkr

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==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==
==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==
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<StructureSection load='1jkr' size='340' side='right' caption='[[1jkr]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
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<StructureSection load='1jkr' size='340' side='right'caption='[[1jkr]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1jkr]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1jkr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JKR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hcr|1hcr]], [[1ijw|1ijw]], [[1jj6|1jj6]], [[1jj8|1jj8]], [[1jko|1jko]], [[1jkp|1jkp]], [[1jkq|1jkq]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkr OCA], [http://pdbe.org/1jkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jkr RCSB], [http://www.ebi.ac.uk/pdbsum/1jkr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkr OCA], [https://pdbe.org/1jkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jkr RCSB], [https://www.ebi.ac.uk/pdbsum/1jkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY]] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
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[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1jkr" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1jkr" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chiu, T K]]
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[[Category: Large Structures]]
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[[Category: Dickerson, R E]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Johnson, R C]]
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[[Category: Chiu TK]]
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[[Category: Sohn, C]]
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[[Category: Dickerson RE]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Johnson RC]]
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[[Category: Hin recombinase]]
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[[Category: Sohn C]]
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[[Category: Protein-dna complex]]
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[[Category: T11c mutant]]
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[[Category: Water-mediated recognition]]
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Current revision

Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations

PDB ID 1jkr

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