5x89

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==The X-ray crystal structure of subunit fusion RNA splicing endonuclease from Methanopyrus kandleri==
==The X-ray crystal structure of subunit fusion RNA splicing endonuclease from Methanopyrus kandleri==
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<StructureSection load='5x89' size='340' side='right' caption='[[5x89]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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<StructureSection load='5x89' size='340' side='right'caption='[[5x89]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5x89]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X89 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5x89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanopyrus_kandleri_AV19 Methanopyrus kandleri AV19]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X89 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA-intron_lyase tRNA-intron lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.16 4.6.1.16] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x89 OCA], [http://pdbe.org/5x89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x89 RCSB], [http://www.ebi.ac.uk/pdbsum/5x89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x89 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x89 OCA], [https://pdbe.org/5x89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x89 RCSB], [https://www.ebi.ac.uk/pdbsum/5x89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x89 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENDA_METKA ENDA_METKA] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.[HAMAP-Rule:MF_01833][https://www.uniprot.org/uniprot/ENDAL_METKA ENDAL_METKA]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: TRNA-intron lyase]]
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[[Category: Large Structures]]
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[[Category: Fujishima, K]]
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[[Category: Methanopyrus kandleri AV19]]
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[[Category: Hirata, A]]
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[[Category: Fujishima K]]
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[[Category: Hori, H]]
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[[Category: Hirata A]]
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[[Category: Kaneta, A]]
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[[Category: Hori H]]
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[[Category: Morikazu, W]]
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[[Category: Kaneta A]]
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[[Category: Archaea]]
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[[Category: Morikazu W]]
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[[Category: Hydrolase]]
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[[Category: Intron]]
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[[Category: Rna splicing]]
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Current revision

The X-ray crystal structure of subunit fusion RNA splicing endonuclease from Methanopyrus kandleri

PDB ID 5x89

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