6bev
From Proteopedia
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==Human Single Domain Sulfurtranferase TSTD1== | ==Human Single Domain Sulfurtranferase TSTD1== | ||
| - | <StructureSection load='6bev' size='340' side='right' caption='[[6bev]], [[Resolution|resolution]] 1.04Å' scene=''> | + | <StructureSection load='6bev' size='340' side='right'caption='[[6bev]], [[Resolution|resolution]] 1.04Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6bev]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BEV OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6bev]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BEV FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.043Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bev OCA], [https://pdbe.org/6bev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bev RCSB], [https://www.ebi.ac.uk/pdbsum/6bev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bev ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TSTD1_HUMAN TSTD1_HUMAN] Thiosulfate:glutathione sulfurtransferase (TST) required to produce glutathione persulfide (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed:24981631). Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide:quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate (PubMed:24981631). The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor (PubMed:24981631).<ref>PMID:24981631</ref> |
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| + | ==See Also== | ||
| + | *[[Sulfurtransferase|Sulfurtransferase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Akey DL]] |
| - | [[Category: | + | [[Category: Banerjee R]] |
| - | [[Category: | + | [[Category: Motl N]] |
| - | [[Category: | + | [[Category: Smith JL]] |
Current revision
Human Single Domain Sulfurtranferase TSTD1
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