2a4g
From Proteopedia
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==Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound== | ==Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound== | ||
| - | <StructureSection load='2a4g' size='340' side='right' caption='[[2a4g]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='2a4g' size='340' side='right'caption='[[2a4g]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2a4g]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2a4g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_hominis Hepacivirus hominis] and [https://en.wikipedia.org/wiki/Hepatitis_C_virus_subtype_1b Hepatitis C virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A4G FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNH:({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC+ACID+ISOBUTYL+ESTER'>UNH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNH:({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC+ACID+ISOBUTYL+ESTER'>UNH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a4g OCA], [https://pdbe.org/2a4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a4g RCSB], [https://www.ebi.ac.uk/pdbsum/2a4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a4g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9QP61_9HEPC Q9QP61_9HEPC] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 2a4g" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2a4g" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Helicase 3D structures|Helicase 3D structures]] | ||
| + | *[[Virus protease 3D structures|Virus protease 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Arasappan | + | [[Category: Hepacivirus hominis]] |
| - | [[Category: Bennett | + | [[Category: Hepatitis C virus subtype 1b]] |
| - | [[Category: Bogen | + | [[Category: Large Structures]] |
| - | [[Category: Butkiewicz | + | [[Category: Arasappan A]] |
| - | [[Category: Chan | + | [[Category: Bennett F]] |
| - | [[Category: Chen | + | [[Category: Bogen SL]] |
| - | [[Category: Ganguly | + | [[Category: Butkiewicz N]] |
| - | [[Category: Girijavallabhan | + | [[Category: Chan TY]] |
| - | [[Category: Gu | + | [[Category: Chen K]] |
| - | [[Category: Hong | + | [[Category: Ganguly AK]] |
| - | [[Category: Ingram | + | [[Category: Girijavallabhan V]] |
| - | [[Category: Jao | + | [[Category: Gu H]] |
| - | [[Category: Kemp | + | [[Category: Hong L]] |
| - | [[Category: Levy | + | [[Category: Ingram R]] |
| - | [[Category: Lim-Wilby | + | [[Category: Jao E]] |
| - | [[Category: Liu | + | [[Category: Kemp S]] |
| - | [[Category: Lovey | + | [[Category: Levy O]] |
| - | [[Category: Madison | + | [[Category: Lim-Wilby M]] |
| - | [[Category: Malcolm | + | [[Category: Liu YT]] |
| - | [[Category: Marten | + | [[Category: Lovey RG]] |
| - | [[Category: Mckittrick | + | [[Category: Madison V]] |
| - | [[Category: Njoroge | + | [[Category: Malcolm B]] |
| - | [[Category: Parekh | + | [[Category: Marten B]] |
| - | [[Category: Pichardo | + | [[Category: Mckittrick B]] |
| - | [[Category: Pike | + | [[Category: Njoroge FG]] |
| - | [[Category: Pinto | + | [[Category: Parekh T]] |
| - | [[Category: Prongay | + | [[Category: Pichardo J]] |
| - | [[Category: Saksena | + | [[Category: Pike RE]] |
| - | [[Category: Santhanam | + | [[Category: Pinto P]] |
| - | [[Category: Tamura | + | [[Category: Prongay AJ]] |
| - | [[Category: Vaccaro | + | [[Category: Saksena AK]] |
| - | [[Category: Venkatraman | + | [[Category: Santhanam B]] |
| - | [[Category: Wang | + | [[Category: Tamura S]] |
| - | [[Category: Yang | + | [[Category: Vaccaro H]] |
| - | [[Category: Yao | + | [[Category: Venkatraman S]] |
| - | [[Category: Zhu | + | [[Category: Wang H]] |
| - | + | [[Category: Yang X]] | |
| + | [[Category: Yao N]] | ||
| + | [[Category: Zhu Z]] | ||
Current revision
Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound
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Categories: Hepacivirus hominis | Hepatitis C virus subtype 1b | Large Structures | Arasappan A | Bennett F | Bogen SL | Butkiewicz N | Chan TY | Chen K | Ganguly AK | Girijavallabhan V | Gu H | Hong L | Ingram R | Jao E | Kemp S | Levy O | Lim-Wilby M | Liu YT | Lovey RG | Madison V | Malcolm B | Marten B | Mckittrick B | Njoroge FG | Parekh T | Pichardo J | Pike RE | Pinto P | Prongay AJ | Saksena AK | Santhanam B | Tamura S | Vaccaro H | Venkatraman S | Wang H | Yang X | Yao N | Zhu Z
