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2biv

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==Crystal structure of the wild-type MBT domains of Human SCML2==
==Crystal structure of the wild-type MBT domains of Human SCML2==
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<StructureSection load='2biv' size='340' side='right' caption='[[2biv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='2biv' size='340' side='right'caption='[[2biv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2biv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2biv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BIV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oi1|1oi1]], [[2vyt|2vyt]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2biv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2biv OCA], [http://pdbe.org/2biv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2biv RCSB], [http://www.ebi.ac.uk/pdbsum/2biv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2biv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2biv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2biv OCA], [https://pdbe.org/2biv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2biv RCSB], [https://www.ebi.ac.uk/pdbsum/2biv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2biv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCML2_HUMAN SCML2_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
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[https://www.uniprot.org/uniprot/SCML2_HUMAN SCML2_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Allen, M D]]
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[[Category: Large Structures]]
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[[Category: Bycroft, M]]
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[[Category: Allen MD]]
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[[Category: Sait, F]]
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[[Category: Bycroft M]]
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[[Category: Santiveri, C M]]
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[[Category: Sait F]]
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[[Category: Malignant brain tumor]]
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[[Category: Santiveri CM]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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Current revision

Crystal structure of the wild-type MBT domains of Human SCML2

PDB ID 2biv

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