2p5u

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==Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD==
==Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD==
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<StructureSection load='2p5u' size='340' side='right' caption='[[2p5u]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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<StructureSection load='2p5u' size='340' side='right'caption='[[2p5u]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2p5u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P5U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2p5u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P5U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0591 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_4-epimerase UDP-glucose 4-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5u OCA], [https://pdbe.org/2p5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p5u RCSB], [https://www.ebi.ac.uk/pdbsum/2p5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5u ProSAT], [https://www.topsan.org/Proteins/RSGI/2p5u TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5u OCA], [http://pdbe.org/2p5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p5u RCSB], [http://www.ebi.ac.uk/pdbsum/2p5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5u ProSAT], [http://www.topsan.org/Proteins/RSGI/2p5u TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SKQ2_THET8 Q5SKQ2_THET8]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5u ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5u ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[UDP-galactose 4-epimerase|UDP-galactose 4-epimerase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thet8]]
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[[Category: Large Structures]]
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[[Category: UDP-glucose 4-epimerase]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Chrzas, J]]
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[[Category: Chrzas J]]
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[[Category: Dillard, B]]
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[[Category: Dillard B]]
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[[Category: Ebihara, A]]
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[[Category: Ebihara A]]
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[[Category: Fu, Z Q]]
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[[Category: Fu Z-Q]]
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[[Category: Kuramitsu, S]]
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[[Category: Kuramitsu S]]
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[[Category: Structural genomic]]
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[[Category: Rose JP]]
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[[Category: Rose, J P]]
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[[Category: Shinkai A]]
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[[Category: Shinkai, A]]
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[[Category: Wang B-C]]
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[[Category: Wang, B C]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Zhao M]]
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[[Category: Zhao, M]]
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[[Category: Isomerase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Rsgi]]
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[[Category: Secsg]]
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[[Category: Thermus thermophilus hb8]]
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[[Category: Ttha0591]]
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[[Category: Udp-glucose 4-epimerase]]
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Current revision

Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD

PDB ID 2p5u

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