5f6q

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==Crystal Structure of Metallothiol Transferase from Bacillus anthracis str. Ames==
==Crystal Structure of Metallothiol Transferase from Bacillus anthracis str. Ames==
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<StructureSection load='5f6q' size='340' side='right' caption='[[5f6q]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
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<StructureSection load='5f6q' size='340' side='right'caption='[[5f6q]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5f6q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F6Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5f6q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F6Q FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fosB2, fosB-2, BA_4109, GBAA_4109, BAS3818 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f6q OCA], [http://pdbe.org/5f6q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f6q RCSB], [http://www.ebi.ac.uk/pdbsum/5f6q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f6q ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f6q OCA], [https://pdbe.org/5f6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f6q RCSB], [https://www.ebi.ac.uk/pdbsum/5f6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f6q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN]] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512]
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[https://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512]
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==See Also==
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*[[Metallothiol transferase FosB|Metallothiol transferase FosB]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anderson, W F]]
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[[Category: Bacillus anthracis]]
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[[Category: Structural genomic]]
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[[Category: Large Structures]]
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[[Category: Joachimiak, A]]
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[[Category: Anderson WF]]
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[[Category: Kim, Y]]
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[[Category: Joachimiak A]]
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[[Category: Maltseva, N]]
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[[Category: Kim Y]]
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[[Category: Osipiuk, J]]
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[[Category: Maltseva N]]
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[[Category: Alpha-beta fold]]
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[[Category: Osipiuk J]]
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[[Category: Csgid]]
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[[Category: Psi-biology]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Metallothiol Transferase from Bacillus anthracis str. Ames

PDB ID 5f6q

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