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2dt5

From Proteopedia

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[[Image:2dt5.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8==
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|PDB= 2dt5 |SIZE=350|CAPTION= <scene name='initialview01'>2dt5</scene>, resolution 2.16&Aring;
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<StructureSection load='2dt5' size='340' side='right'caption='[[2dt5]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2dt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DT5 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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|GENE= TTHA1657 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dt5 OCA], [https://pdbe.org/2dt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2dt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dt5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dt5 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dt5 OCA], [http://www.ebi.ac.uk/pdbsum/2dt5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dt5 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/REX_THET8 REX_THET8] Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.[HAMAP-Rule:MF_01131]
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== Evolutionary Conservation ==
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'''Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dt5_consurf.spt"</scriptWhenChecked>
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2DT5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT5 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of TTHA1657 (AT-rich DNA-binding protein; p25) from Thermus thermophilus HB8 at 2.16 A resolution., Nakamura A, Sosa A, Komori H, Kita A, Miki K, Proteins. 2007 Feb 15;66(3):755-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17154156 17154156]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dt5 ConSurf].
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[[Category: Single protein]]
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<div style="clear:both"></div>
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[[Category: Thermus thermophilus]]
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__TOC__
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[[Category: Kita, A.]]
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</StructureSection>
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[[Category: Komori, H.]]
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[[Category: Large Structures]]
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[[Category: Miki, K.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Nakamura, A.]]
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[[Category: Kita A]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Komori H]]
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[[Category: Sosa, A.]]
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[[Category: Miki K]]
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[[Category: nad]]
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[[Category: Nakamura A]]
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[[Category: nadh]]
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[[Category: Sosa A]]
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[[Category: redox sensing]]
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[[Category: rex]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rossmann fold]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: thermus themophilus]]
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[[Category: winged helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:39:10 2008''
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Current revision

Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8

PDB ID 2dt5

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