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1l2w

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==Crystal Structure of the Yersinia Virulence Effector YopE Chaperone-binding Domain in Complex with its Secretion Chaperone, SycE==
==Crystal Structure of the Yersinia Virulence Effector YopE Chaperone-binding Domain in Complex with its Secretion Chaperone, SycE==
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<StructureSection load='1l2w' size='340' side='right' caption='[[1l2w]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1l2w' size='340' side='right'caption='[[1l2w]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1l2w]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudotuberkulosis"_(sic)_pfeiffer_1889 "bacillus pseudotuberkulosis" (sic) pfeiffer 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L2W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1l2w]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pseudotuberculosis Yersinia pseudotuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L2W FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">syce ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=633 "Bacillus pseudotuberkulosis" (sic) Pfeiffer 1889]), yope ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=633 "Bacillus pseudotuberkulosis" (sic) Pfeiffer 1889])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l2w OCA], [http://pdbe.org/1l2w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l2w RCSB], [http://www.ebi.ac.uk/pdbsum/1l2w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l2w ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l2w OCA], [https://pdbe.org/1l2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l2w RCSB], [https://www.ebi.ac.uk/pdbsum/1l2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l2w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/YOPE_YERPS YOPE_YERPS]] Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis.
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[https://www.uniprot.org/uniprot/A0A0N9NJF3_YERPU A0A0N9NJF3_YERPU] Positive regulator of YopE.[PIRNR:PIRNR011271]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Birtalan, S C]]
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[[Category: Large Structures]]
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[[Category: Ghosh, P]]
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[[Category: Yersinia pseudotuberculosis]]
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[[Category: Phillips, R M]]
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[[Category: Birtalan SC]]
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[[Category: Chaperone]]
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[[Category: Ghosh P]]
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[[Category: Chaperone and virulence protein]]
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[[Category: Phillips RM]]

Current revision

Crystal Structure of the Yersinia Virulence Effector YopE Chaperone-binding Domain in Complex with its Secretion Chaperone, SycE

PDB ID 1l2w

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