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(→Crystal structure of the µ-opioid receptor bound to a morphinan antagonist) |
(→Crystal structure of the µ-opioid receptor bound to a morphinan antagonist) |
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<StructureSection load='' size='340' side='right' caption='Click a green link on the left to load Figure 1' scene=''> | <StructureSection load='' size='340' side='right' caption='Click a green link on the left to load Figure 1' scene=''> | ||
'''Figure 1: Overall view of the µ-OR structure''' | '''Figure 1: Overall view of the µ-OR structure''' | ||
| + | see [https://www.nature.com/articles/nature10954 the paper] for essentially this exact figure. | ||
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Shown in <jmol><jmollink><text>Figure 1</text><script>exit;figure="http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png";SCRIPT @figure</script></jmollink></jmol> is an overall view of the µ-opioid receptor bound to the morphinan antagonist ([https://chemapps.stolaf.edu/jmol/jmol.php?pdbid=BF0&script=set%20echo%20top%20left;echo%20PDBid%20BF0;spin%20on PDBid BF0]). The seven parallel trans-membrane helices are the signature of a "TM7" cell membrane receptor, spanning the 35-40 nm distance across the lipid bilayer of the cell. | Shown in <jmol><jmollink><text>Figure 1</text><script>exit;figure="http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png";SCRIPT @figure</script></jmollink></jmol> is an overall view of the µ-opioid receptor bound to the morphinan antagonist ([https://chemapps.stolaf.edu/jmol/jmol.php?pdbid=BF0&script=set%20echo%20top%20left;echo%20PDBid%20BF0;spin%20on PDBid BF0]). The seven parallel trans-membrane helices are the signature of a "TM7" cell membrane receptor, spanning the 35-40 nm distance across the lipid bilayer of the cell. | ||
Current revision
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
[https://www.nature.com/articles/nature10954 Nature volume 485, pages 321–326 (17 May 2012) doi:10.1038/nature10954]
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code for the above (space inserted just after the : <jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol>
is a close-up view of a bound to the µ-opioid receptor. The green circles indicate hydrogen bonds.
