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2dyq

From Proteopedia

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[[Image:2dyq.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3==
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|PDB= 2dyq |SIZE=350|CAPTION= <scene name='initialview01'>2dyq</scene>, resolution 3.10&Aring;
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<StructureSection load='2dyq' size='340' side='right'caption='[[2dyq]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[2dyq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYQ FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|GENE= APBB3, FE65L2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBB3, FE65L2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyq OCA], [https://pdbe.org/2dyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyq RCSB], [https://www.ebi.ac.uk/pdbsum/2dyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyq ProSAT], [https://www.topsan.org/Proteins/RSGI/2dyq TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyq OCA], [http://www.ebi.ac.uk/pdbsum/2dyq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dyq RCSB]</span>
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== Function ==
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}}
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[[https://www.uniprot.org/uniprot/APBB3_HUMAN APBB3_HUMAN]] May modulate the internalization of beta-amyloid precursor protein.
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== Evolutionary Conservation ==
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'''Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyq_consurf.spt"</scriptWhenChecked>
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2DYQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYQ OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Homo sapiens]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Kishishita, S.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyq ConSurf].
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[[Category: Nishino, A.]]
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<div style="clear:both"></div>
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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__TOC__
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[[Category: Saijo, S.]]
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</StructureSection>
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[[Category: Shirouzu, M.]]
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[[Category: Human]]
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[[Category: Yokoyama, S.]]
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[[Category: Large Structures]]
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[[Category: alzheimer's disease]]
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[[Category: Kishishita, S]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: Nishino, A]]
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[[Category: nppsfa]]
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[[Category: Structural genomic]]
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[[Category: phosphotyrosine-interaction domain (ptb/pid)]]
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[[Category: Saijo, S]]
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[[Category: protein binding]]
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[[Category: Shirouzu, M]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: Yokoyama, S]]
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[[Category: rsgi]]
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[[Category: Alzheimer's disease]]
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[[Category: structural genomic]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:41:21 2008''
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[[Category: Protein binding]]
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[[Category: Rsgi]]

Current revision

Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3

PDB ID 2dyq

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