2dyu

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[[Image:2dyu.gif|left|200px]]
 
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{{Structure
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==Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad==
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|PDB= 2dyu |SIZE=350|CAPTION= <scene name='initialview01'>2dyu</scene>, resolution 1.75&Aring;
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<StructureSection load='2dyu' size='340' side='right'caption='[[2dyu]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2dyu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYU FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Formamidase Formamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.49 3.5.1.49] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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|GENE= amiF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyu OCA], [https://pdbe.org/2dyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyu RCSB], [https://www.ebi.ac.uk/pdbsum/2dyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyu ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[2dyv|2DYV]], [[2e2k|2E2K]], [[2e2l|2E2L]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyu OCA], [http://www.ebi.ac.uk/pdbsum/2dyu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dyu RCSB]</span>
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[https://www.uniprot.org/uniprot/AMIF_HELPY AMIF_HELPY] Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide. Probably involved in the nitrogen metabolism of H.pylori.<ref>PMID:11359566</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyu_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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2DYU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYU OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Formamidase]]
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</jmolCheckbox>
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[[Category: Helicobacter pylori]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyu ConSurf].
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[[Category: Single protein]]
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<div style="clear:both"></div>
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[[Category: Hung, C L.]]
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== References ==
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[[Category: Wang, W C.]]
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<references/>
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[[Category: aliphatic amidase]]
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__TOC__
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[[Category: amif]]
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</StructureSection>
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[[Category: catalytic triad]]
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[[Category: Helicobacter pylori 26695]]
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[[Category: cek]]
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[[Category: Large Structures]]
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[[Category: formamidase]]
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[[Category: Hung CL]]
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[[Category: helicobacter pylori]]
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[[Category: Wang WC]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:41:24 2008''
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Current revision

Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad

PDB ID 2dyu

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