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2dzk
From Proteopedia
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| - | [[Image:2dzk.jpg|left|200px]] | ||
| - | + | ==Structure of the UBX domain in Mouse UBX Domain-Containing Protein 2== | |
| - | + | <StructureSection load='2dzk' size='340' side='right'caption='[[2dzk]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2dzk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzk OCA], [https://pdbe.org/2dzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzk RCSB], [https://www.ebi.ac.uk/pdbsum/2dzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzk ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzk TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | | | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/UBXN4_MOUSE UBXN4_MOUSE] Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.[UniProtKB:Q92575] | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/2dzk_consurf.spt"</scriptWhenChecked> | |
| - | == | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dzk ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Harada T]] | |
| - | [[Category: Harada | + | [[Category: Kigawa T]] |
| - | [[Category: Kigawa | + | [[Category: Koshiba S]] |
| - | [[Category: Koshiba | + | [[Category: Watanabe S]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Watanabe | + | [[Category: Yoneyama M]] |
| - | [[Category: Yokoyama | + | [[Category: Zhao C]] |
| - | [[Category: Yoneyama | + | |
| - | [[Category: Zhao | + | |
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Current revision
Structure of the UBX domain in Mouse UBX Domain-Containing Protein 2
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Categories: Large Structures | Mus musculus | Harada T | Kigawa T | Koshiba S | Watanabe S | Yokoyama S | Yoneyama M | Zhao C
