This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2q3e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:17, 30 August 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose==
==Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose==
-
<StructureSection load='2q3e' size='340' side='right' caption='[[2q3e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+
<StructureSection load='2q3e' size='340' side='right'caption='[[2q3e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2q3e]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q3E FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2q3e]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q3E FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UGDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_6-dehydrogenase UDP-glucose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.22 1.1.1.22] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q3e OCA], [https://pdbe.org/2q3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q3e RCSB], [https://www.ebi.ac.uk/pdbsum/2q3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q3e ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q3e OCA], [http://pdbe.org/2q3e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q3e RCSB], [http://www.ebi.ac.uk/pdbsum/2q3e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2q3e ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/UGDH_HUMAN UGDH_HUMAN]] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
+
[https://www.uniprot.org/uniprot/UGDH_HUMAN UGDH_HUMAN] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 30: Line 29:
</div>
</div>
<div class="pdbe-citations 2q3e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2q3e" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: UDP-glucose 6-dehydrogenase]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C]]
+
[[Category: Arrowsmith C]]
-
[[Category: Berridge, G]]
+
[[Category: Berridge G]]
-
[[Category: Bhatia, C]]
+
[[Category: Bhatia C]]
-
[[Category: Bunkoczi, G]]
+
[[Category: Bunkoczi G]]
-
[[Category: Delft, F von]]
+
[[Category: Edwards A]]
-
[[Category: Edwards, A]]
+
[[Category: Guo K]]
-
[[Category: Guo, K]]
+
[[Category: Kavanagh KL]]
-
[[Category: Kavanagh, K L]]
+
[[Category: Oppermann U]]
-
[[Category: Oppermann, U]]
+
[[Category: Pilka E]]
-
[[Category: Pilka, E]]
+
[[Category: Savitsky P]]
-
[[Category: Structural genomic]]
+
[[Category: Smee C]]
-
[[Category: Savitsky, P]]
+
[[Category: Sundstrom M]]
-
[[Category: Smee, C]]
+
[[Category: Wiegelt J]]
-
[[Category: Sundstrom, M]]
+
[[Category: Von Delft F]]
-
[[Category: Wiegelt, J]]
+
-
[[Category: Hexamer]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Udp-glucose 6-dehydrogenase]]
+

Current revision

Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose

PDB ID 2q3e

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2q3e"
Personal tools