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5uwc

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==Cytokine-receptor complex==
==Cytokine-receptor complex==
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<StructureSection load='5uwc' size='340' side='right' caption='[[5uwc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='5uwc' size='340' side='right'caption='[[5uwc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5uwc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UWC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5uwc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UWC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDT:{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC+ACID'>EDT</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uv8|5uv8]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDT:{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC+ACID'>EDT</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uwc OCA], [http://pdbe.org/5uwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uwc RCSB], [http://www.ebi.ac.uk/pdbsum/5uwc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uwc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uwc OCA], [https://pdbe.org/5uwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uwc RCSB], [https://www.ebi.ac.uk/pdbsum/5uwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uwc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IL3RA_HUMAN IL3RA_HUMAN]] This is a receptor for interleukin-3. [[http://www.uniprot.org/uniprot/IL3_HUMAN IL3_HUMAN]] Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
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[https://www.uniprot.org/uniprot/IL3RA_HUMAN IL3RA_HUMAN] This is a receptor for interleukin-3.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5uwc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5uwc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Interleukin 3D structures|Interleukin 3D structures]]
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*[[Interleukin receptor 3D structures|Interleukin receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Broughton, S E]]
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[[Category: Homo sapiens]]
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[[Category: Parker, M W]]
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[[Category: Large Structures]]
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[[Category: Cytokine]]
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[[Category: Broughton SE]]
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[[Category: Receptor]]
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[[Category: Parker MW]]
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[[Category: Signaling protein]]
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[[Category: Signalling]]
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Current revision

Cytokine-receptor complex

PDB ID 5uwc

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