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1nwa

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==Structure of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A in Complex with Protein-bound Methionine==
==Structure of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A in Complex with Protein-bound Methionine==
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<StructureSection load='1nwa' size='340' side='right' caption='[[1nwa]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='1nwa' size='340' side='right'caption='[[1nwa]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1nwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NWA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1nwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NWA FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-methionine_(S)-S-oxide_reductase Peptide-methionine (S)-S-oxide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.11 1.8.4.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nwa OCA], [https://pdbe.org/1nwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nwa RCSB], [https://www.ebi.ac.uk/pdbsum/1nwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nwa ProSAT], [https://www.topsan.org/Proteins/TBSGC/1nwa TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nwa OCA], [http://pdbe.org/1nwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nwa RCSB], [http://www.ebi.ac.uk/pdbsum/1nwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nwa ProSAT], [http://www.topsan.org/Proteins/TBSGC/1nwa TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MSRA_MYCTU MSRA_MYCTU]] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
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[https://www.uniprot.org/uniprot/MSRA_MYCTU MSRA_MYCTU] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Benglis, D M]]
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[[Category: Large Structures]]
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[[Category: Dhandayuthapani, S]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Hart, P J]]
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[[Category: Benglis Jr DM]]
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[[Category: Structural genomic]]
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[[Category: Dhandayuthapani S]]
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[[Category: Taylor, A B]]
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[[Category: Hart PJ]]
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[[Category: Oxidoreductase]]
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[[Category: Taylor AB]]
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[[Category: Peptide methionine sulfoxide reductase]]
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[[Category: Product complex]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Tbsgc]]
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Current revision

Structure of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A in Complex with Protein-bound Methionine

PDB ID 1nwa

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