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2efm

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[[Image:2efm.jpg|left|200px]]
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#REDIRECT [[3lxs]] This PDB entry is obsolete and replaced by 3lxs
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{{Structure
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|PDB= 2efm |SIZE=350|CAPTION= <scene name='initialview01'>2efm</scene>, resolution 1.50&Aring;
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|SITE= <scene name='pdbsite=AC1:4mc+Binding+Site+For+Residue+A+1300'>AC1</scene>, <scene name='pdbsite=AC2:4mc+Binding+Site+For+Residue+C+2300'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+1001'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+A+1002'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+C+1003'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+A+1004'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+A+1005'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+C+1006'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+A+1007'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+C+1008'>BC1</scene> and <scene name='pdbsite=BC2:Edo+Binding+Site+For+Residue+A+2960'>BC2</scene>
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|LIGAND= <scene name='pdbligand=4MC:(Z)-N-(5-GUANIDINO-1-OXO-1-(5-PHENYL-1-(PHENYLSULFONYL)PENT-1-EN-3-YLAMINO)PENTAN-2-YL)-4-METHYLPIPERAZINE-1-CARBOXAMIDE'>4MC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cruzipain Cruzipain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.51 3.4.22.51] </span>
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|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efm OCA], [http://www.ebi.ac.uk/pdbsum/2efm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2efm RCSB]</span>
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}}
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'''crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (WR483)'''
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==About this Structure==
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2EFM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFM OCA].
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[[Category: Cruzipain]]
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[[Category: Single protein]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Brinen, L.]]
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[[Category: Rickert, M.]]
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[[Category: covalent inhibitor]]
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[[Category: cysteine protease]]
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[[Category: hydrolase]]
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[[Category: vinyl sulfonamide derived]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:48:18 2008''
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Current revision

  1. REDIRECT 3lxs This PDB entry is obsolete and replaced by 3lxs

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