6ccf

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m (Protected "6ccf" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6ccf is ON HOLD
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==Crystal Structure of the Human CAMKK1A in complex with Hesperadin==
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<StructureSection load='6ccf' size='340' side='right'caption='[[6ccf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ccf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CCF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=H1N:N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE'>H1N</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ccf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ccf OCA], [https://pdbe.org/6ccf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ccf RCSB], [https://www.ebi.ac.uk/pdbsum/6ccf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ccf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KKCC1_HUMAN KKCC1_HUMAN] Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.<ref>PMID:12935886</ref>
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Authors: Santiago, A.S., Counago, R.M., dos Reis, C.V., Ramos, P.Z., Drewry, D., Elkins, J.M., Massirer, K.B., Arruda, P., Edwards, A.M., Structural Genomics Consortium (SGC)
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==See Also==
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*[[Calcium/calmodulin-dependent protein kinase kinase|Calcium/calmodulin-dependent protein kinase kinase]]
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Description: Crystal Structure of the Human CAMKK1A in complex with Hesperadin
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Elkins, J.M]]
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__TOC__
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[[Category: Massirer, K.B]]
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</StructureSection>
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[[Category: Counago, R.M]]
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[[Category: Homo sapiens]]
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[[Category: Dos Reis, C.V]]
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[[Category: Large Structures]]
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[[Category: Drewry, D]]
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[[Category: Arruda P]]
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[[Category: Edwards, A.M]]
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[[Category: Counago RM]]
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[[Category: Arruda, P]]
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[[Category: Drewry D]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Edwards AM]]
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[[Category: Santiago, A.S]]
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[[Category: Elkins JM]]
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[[Category: Ramos, P.Z]]
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[[Category: Massirer KB]]
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[[Category: Ramos PZ]]
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[[Category: Santiago AS]]
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[[Category: Silva PNB]]
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[[Category: Dos Reis CV]]

Current revision

Crystal Structure of the Human CAMKK1A in complex with Hesperadin

PDB ID 6ccf

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