6ccs
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6ccs is ON HOLD Authors: Mamo, M., Appleton, B.A. Description: Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in co...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 2-(trifluoromethyl)-1H-benzo[d]imidazol-4-ol== | |
| - | + | <StructureSection load='6ccs' size='340' side='right'caption='[[6ccs]], [[Resolution|resolution]] 2.06Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ccs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CCS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EXD:2-(trifluoromethyl)-1H-benzimidazol-7-ol'>EXD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: Appleton | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ccs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ccs OCA], [https://pdbe.org/6ccs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ccs RCSB], [https://www.ebi.ac.uk/pdbsum/6ccs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ccs ProSAT]</span></td></tr> |
| - | [[Category: Mamo | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/COAD_ECOLI COAD_ECOLI] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Appleton BA]] | ||
| + | [[Category: Mamo M]] | ||
Current revision
Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 2-(trifluoromethyl)-1H-benzo[d]imidazol-4-ol
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