6cd6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6cd6" [edit=sysop:move=sysop])
Current revision (15:01, 4 October 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6cd6 is ON HOLD
+
==Crystal Structure of the Human CAMKK1A in complex with GSK650394==
 +
<StructureSection load='6cd6' size='340' side='right'caption='[[6cd6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[6cd6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CD6 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DXV:2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic+acid'>DXV</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cd6 OCA], [https://pdbe.org/6cd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cd6 RCSB], [https://www.ebi.ac.uk/pdbsum/6cd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cd6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KKCC1_HUMAN KKCC1_HUMAN] Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.<ref>PMID:12935886</ref>
-
Authors: Santiago, A.S., Counago, R.M., Righetto, G.L., Ramos, P.Z., Silva, P.N.B., Drewry, D., Elkins, J.M., Massirer, K.B., Arruda, P., Edwards, A.M., Structural Genomics Consortium (SGC)
+
==See Also==
-
 
+
*[[Calcium/calmodulin-dependent protein kinase kinase|Calcium/calmodulin-dependent protein kinase kinase]]
-
Description: Crystal Structure of the Human CAMKK1A in complex with GSK650394
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
-
[[Category: Righetto, G.L]]
+
__TOC__
-
[[Category: Elkins, J.M]]
+
</StructureSection>
-
[[Category: Massirer, K.B]]
+
[[Category: Homo sapiens]]
-
[[Category: Counago, R.M]]
+
[[Category: Large Structures]]
-
[[Category: Drewry, D]]
+
[[Category: Arruda P]]
-
[[Category: Edwards, A.M]]
+
[[Category: Counago RM]]
-
[[Category: Silva, P.N.B]]
+
[[Category: Drewry D]]
-
[[Category: Arruda, P]]
+
[[Category: Edwards AM]]
-
[[Category: Structural Genomics Consortium (Sgc)]]
+
[[Category: Elkins JM]]
-
[[Category: Santiago, A.S]]
+
[[Category: Massirer KB]]
-
[[Category: Ramos, P.Z]]
+
[[Category: Ramos PZ]]
 +
[[Category: Righetto GL]]
 +
[[Category: Santiago AS]]
 +
[[Category: Silva PNB]]

Current revision

Crystal Structure of the Human CAMKK1A in complex with GSK650394

PDB ID 6cd6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6cd6"
Personal tools