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2ejc

From Proteopedia

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[[Image:2ejc.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima==
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|PDB= 2ejc |SIZE=350|CAPTION= <scene name='initialview01'>2ejc</scene>, resolution 2.40&Aring;
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<StructureSection load='2ejc' size='340' side='right'caption='[[2ejc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+502'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+A+503'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+A+504'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+A+505'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+A+506'>AC6</scene>, <scene name='pdbsite=AC7:Zn+Binding+Site+For+Residue+A+507'>AC7</scene>, <scene name='pdbsite=AC8:Zn+Binding+Site+For+Residue+A+508'>AC8</scene>, <scene name='pdbsite=AC9:Zn+Binding+Site+For+Residue+A+509'>AC9</scene>, <scene name='pdbsite=BC1:Zn+Binding+Site+For+Residue+A+510'>BC1</scene>, <scene name='pdbsite=BC2:Zn+Binding+Site+For+Residue+A+511'>BC2</scene>, <scene name='pdbsite=BC3:Zn+Binding+Site+For+Residue+A+512'>BC3</scene>, <scene name='pdbsite=BC4:Zn+Binding+Site+For+Residue+A+513'>BC4</scene>, <scene name='pdbsite=BC5:Zn+Binding+Site+For+Residue+A+515'>BC5</scene>, <scene name='pdbsite=BC6:Zn+Binding+Site+For+Residue+A+516'>BC6</scene>, <scene name='pdbsite=BC7:Zn+Binding+Site+For+Residue+A+517'>BC7</scene>, <scene name='pdbsite=BC8:Zn+Binding+Site+For+Residue+A+518'>BC8</scene>, <scene name='pdbsite=BC9:Zn+Binding+Site+For+Residue+A+519'>BC9</scene>, <scene name='pdbsite=CC1:Zn+Binding+Site+For+Residue+A+521'>CC1</scene>, <scene name='pdbsite=CC2:Zn+Binding+Site+For+Residue+A+522'>CC2</scene> and <scene name='pdbsite=CC3:Act+Binding+Site+For+Residue+A+1101'>CC3</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[2ejc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EJC FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE= panC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ejc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejc OCA], [https://pdbe.org/2ejc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ejc RCSB], [https://www.ebi.ac.uk/pdbsum/2ejc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ejc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ejc TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ejc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejc OCA], [http://www.ebi.ac.uk/pdbsum/2ejc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ejc RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PANC_THEMA PANC_THEMA] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2ejc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ejc ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima'''
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==See Also==
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*[[Pantothenate synthetase|Pantothenate synthetase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2EJC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJC OCA].
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[[Category: Large Structures]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Single protein]]
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Bagautdinov, B.]]
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[[Category: Bagautdinov B]]
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[[Category: Kunishima, N.]]
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[[Category: Kunishima N]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: nppsfa]]
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[[Category: pantoate-beta-alanine ligase]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: x-ray diffraction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:49:59 2008''
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Current revision

Crystal Structure Of Pantoate--Beta-Alanine Ligase (panC) From Thermotoga maritima

PDB ID 2ejc

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