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2ejv

From Proteopedia

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[[Image:2ejv.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of threonine 3-dehydrogenase complexed with NAD+==
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|PDB= 2ejv |SIZE=350|CAPTION= <scene name='initialview01'>2ejv</scene>, resolution 2.55&Aring;
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<StructureSection load='2ejv' size='340' side='right'caption='[[2ejv]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+502'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+501'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+502'>AC4</scene>, <scene name='pdbsite=AC5:Nad+Binding+Site+For+Residue+B+2350'>AC5</scene> and <scene name='pdbsite=AC6:Nad+Binding+Site+For+Residue+A+1350'>AC6</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[2ejv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EJV FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/L-threonine_3-dehydrogenase L-threonine 3-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.103 1.1.1.103] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK05396 tdh], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00107 ADH_zinc_N], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08240 ADH_N]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ejv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejv OCA], [https://pdbe.org/2ejv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ejv RCSB], [https://www.ebi.ac.uk/pdbsum/2ejv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ejv ProSAT], [https://www.topsan.org/Proteins/RSGI/2ejv TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ejv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ejv OCA], [http://www.ebi.ac.uk/pdbsum/2ejv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ejv RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/TDH_THET8 TDH_THET8]
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== Evolutionary Conservation ==
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'''Crystal structure of threonine 3-dehydrogenase complexed with NAD+'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2ejv_consurf.spt"</scriptWhenChecked>
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2EJV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJV OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: L-threonine 3-dehydrogenase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Thermus thermophilus]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ejv ConSurf].
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[[Category: Goto, M.]]
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<div style="clear:both"></div>
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[[Category: Hirotsu, K.]]
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__TOC__
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[[Category: Miyahara, I.]]
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</StructureSection>
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[[Category: Omi, R.]]
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[[Category: Large Structures]]
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[[Category: Yao, T.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: nad-dependent]]
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[[Category: Goto M]]
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[[Category: oxidoreductase]]
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[[Category: Hirotsu K]]
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[[Category: Miyahara I]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:50:16 2008''
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[[Category: Omi R]]
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[[Category: Yao T]]

Current revision

Crystal structure of threonine 3-dehydrogenase complexed with NAD+

PDB ID 2ejv

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