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2el9

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[[Image:2el9.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue==
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|PDB= 2el9 |SIZE=350|CAPTION= <scene name='initialview01'>2el9</scene>, resolution 2.70&Aring;
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<StructureSection load='2el9' size='340' side='right'caption='[[2el9]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Hss+Binding+Site+For+Residue+A+510'>AC1</scene>, <scene name='pdbsite=AC2:Hss+Binding+Site+For+Residue+B+610'>AC2</scene>, <scene name='pdbsite=AC3:Hss+Binding+Site+For+Residue+C+710'>AC3</scene> and <scene name='pdbsite=AC4:Hss+Binding+Site+For+Residue+D+810'>AC4</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=HSS:5&#39;-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE'>HSS</scene>
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<table><tr><td colspan='2'>[[2el9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EL9 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine--tRNA_ligase Histidine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.21 6.1.1.21] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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|GENE= hisS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HSS:5-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE'>HSS</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2el9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2el9 OCA], [https://pdbe.org/2el9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2el9 RCSB], [https://www.ebi.ac.uk/pdbsum/2el9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2el9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2el9 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2el9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2el9 OCA], [http://www.ebi.ac.uk/pdbsum/2el9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2el9 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/SYH_ECOLI SYH_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/2el9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2el9 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue'''
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2EL9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EL9 OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Histidine--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Ishii R]]
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[[Category: Ishii, R.]]
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[[Category: Matsuno M]]
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[[Category: Matsuno, M.]]
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[[Category: Si SY]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yanagisawa T]]
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[[Category: Si, S Y.]]
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[[Category: Yokoyama S]]
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[[Category: Yanagisawa, T.]]
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[[Category: Yokoyama, S.]]
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[[Category: aminoacyl-trna synthetase]]
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[[Category: aminoacyladenylate analog]]
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[[Category: histidyl-trna synthetase]]
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[[Category: ligase]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: nppsfa]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: translation]]
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[[Category: trna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:50:45 2008''
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Current revision

Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue

PDB ID 2el9

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