1ott

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:32, 16 August 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex==
==Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex==
-
<StructureSection load='1ott' size='340' side='right' caption='[[1ott]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+
<StructureSection load='1ott' size='340' side='right'caption='[[1ott]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1ott]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTT FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1ott]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTT FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ots|1ots]], [[1otu|1otu]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERIC OR B0155 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ott OCA], [https://pdbe.org/1ott PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ott RCSB], [https://www.ebi.ac.uk/pdbsum/1ott PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ott ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ott FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ott OCA], [http://pdbe.org/1ott PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ott RCSB], [http://www.ebi.ac.uk/pdbsum/1ott PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ott ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI]] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref>
+
[https://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 30: Line 29:
</div>
</div>
<div class="pdbe-citations 1ott" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1ott" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Ion channels 3D structures|Ion channels 3D structures]]
 +
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacillus coli migula 1895]]
+
[[Category: Escherichia coli]]
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Campbell, E B]]
+
[[Category: Campbell EB]]
-
[[Category: Dutzler, R]]
+
[[Category: Dutzler R]]
-
[[Category: MacKinnon, R]]
+
[[Category: MacKinnon R]]
-
[[Category: Chloride channel]]
+
-
[[Category: Fab complex]]
+
-
[[Category: Ion channel]]
+
-
[[Category: Membrane protein]]
+

Current revision

Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex

PDB ID 1ott

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ott"
Personal tools