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2eo8

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[[Image:2eo8.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus==
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|PDB= 2eo8 |SIZE=350|CAPTION= <scene name='initialview01'>2eo8</scene>, resolution 2.30&Aring;
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<StructureSection load='2eo8' size='340' side='right'caption='[[2eo8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2eo8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EO8 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyroglutamyl-peptidase_I Pyroglutamyl-peptidase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.3 3.4.19.3] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo8 OCA], [https://pdbe.org/2eo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eo8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eo8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eo8 TOPSAN]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo8 OCA], [http://www.ebi.ac.uk/pdbsum/2eo8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eo8 RCSB]</span>
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[https://www.uniprot.org/uniprot/PCP_PYRFU PCP_PYRFU] Removes 5-oxoproline from various penultimate amino acid residues except L-proline.[HAMAP-Rule:MF_00417]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo8_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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2EO8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO8 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eo8 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Pyroglutamyl-peptidase I]]
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[[Category: Okazaki N]]
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[[Category: Single protein]]
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[[Category: Sakamoto K]]
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[[Category: Okazaki, N.]]
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[[Category: Yutani K]]
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[[Category: Sakamoto, K.]]
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[[Category: Yutani, K.]]
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[[Category: hydrolase]]
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[[Category: pcp]]
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[[Category: pgp-i]]
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[[Category: protease]]
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[[Category: pyrococcus furiosus]]
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[[Category: pyroglutamyl-peptidase i]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:51:42 2008''
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Current revision

Crystal structure of a mutant pyrrolidone carboxyl peptidase (A199P) from P. furiosus

PDB ID 2eo8

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