2eqa

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[[Image:2eqa.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of the hypothetical Sua5 protein from Sulfolobus tokodaii==
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|PDB= 2eqa |SIZE=350|CAPTION= <scene name='initialview01'>2eqa</scene>, resolution 1.80&Aring;
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<StructureSection load='2eqa' size='340' side='right'caption='[[2eqa]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[2eqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQA FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= SUA5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=111955 Sulfolobus tokodaii])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqa OCA], [https://pdbe.org/2eqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqa RCSB], [https://www.ebi.ac.uk/pdbsum/2eqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqa ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqa TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqa OCA], [http://www.ebi.ac.uk/pdbsum/2eqa PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eqa RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/SUA5_SULTO SUA5_SULTO] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). Probably catalyzes the conversion of L-threonine, bicarbonate/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of pyrophosphate. Shows ATP hydrolysis activity in vitro, producing AMP.<ref>PMID:22383337</ref>
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== Evolutionary Conservation ==
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'''Crystal Structure of the hypothetical Sua5 protein from Sulfolobus tokodaii'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/2eqa_consurf.spt"</scriptWhenChecked>
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2EQA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQA OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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X-ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7., Agari Y, Sato S, Wakamatsu T, Bessho Y, Ebihara A, Yokoyama S, Kuramitsu S, Shinkai A, Proteins. 2008 Feb 15;70(3):1108-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18004774 18004774]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eqa ConSurf].
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[[Category: Single protein]]
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<div style="clear:both"></div>
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[[Category: Sulfolobus tokodaii]]
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== References ==
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[[Category: Agari, Y.]]
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<references/>
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[[Category: Kuramitsu, S.]]
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__TOC__
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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</StructureSection>
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[[Category: Shinkai, A.]]
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[[Category: Large Structures]]
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[[Category: Yokoyama, S.]]
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[[Category: Sulfurisphaera tokodaii]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: Agari Y]]
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[[Category: nppsfa]]
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[[Category: Kuramitsu S]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: Shinkai A]]
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[[Category: rna binding protein]]
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[[Category: Yokoyama S]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: sua5 domain]]
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[[Category: yrdc domain]]
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[[Category: yrdc/ribb fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:52:33 2008''
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Current revision

Crystal Structure of the hypothetical Sua5 protein from Sulfolobus tokodaii

PDB ID 2eqa

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