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5us6

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==Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag==
==Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag==
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<StructureSection load='5us6' size='340' side='right' caption='[[5us6]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
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<StructureSection load='5us6' size='340' side='right'caption='[[5us6]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5us6]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5US6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5us6]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus_CMCP6 Vibrio vulnificus CMCP6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5US6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PDC:PYRIDINE-2,6-DICARBOXYLIC+ACID'>PDC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_reductase 4-hydroxy-tetrahydrodipicolinate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.1.8 1.17.1.8] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PDC:PYRIDINE-2,6-DICARBOXYLIC+ACID'>PDC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5us6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us6 OCA], [http://pdbe.org/5us6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5us6 RCSB], [http://www.ebi.ac.uk/pdbsum/5us6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5us6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5us6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us6 OCA], [https://pdbe.org/5us6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5us6 RCSB], [https://www.ebi.ac.uk/pdbsum/5us6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5us6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DAPB_VIBVU DAPB_VIBVU]] Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.[HAMAP-Rule:MF_00102]
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[https://www.uniprot.org/uniprot/DAPB_VIBVU DAPB_VIBVU] Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.[HAMAP-Rule:MF_00102]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 4-hydroxy-tetrahydrodipicolinate reductase]]
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[[Category: Large Structures]]
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[[Category: Arnette, A K]]
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[[Category: Vibrio vulnificus CMCP6]]
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[[Category: Chruszcz, M]]
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[[Category: Arnette AK]]
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[[Category: Mank, N M]]
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[[Category: Chruszcz M]]
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[[Category: Lysine biosynthesis]]
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[[Category: Mank NM]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag

PDB ID 5us6

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