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6azs

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==Structural and biochemical characterization of a non-canonical biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841==
==Structural and biochemical characterization of a non-canonical biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841==
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<StructureSection load='6azs' size='340' side='right' caption='[[6azs]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
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<StructureSection load='6azs' size='340' side='right'caption='[[6azs]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6azs]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AZS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6azs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_leguminosarum_bv._viciae_3841 Rhizobium leguminosarum bv. viciae 3841]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AZS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=C5S:N-formyl-D-aspartic+acid'>C5S</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6azs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6azs OCA], [http://pdbe.org/6azs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6azs RCSB], [http://www.ebi.ac.uk/pdbsum/6azs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6azs ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=C5S:N-formyl-D-aspartic+acid'>C5S</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6azs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6azs OCA], [https://pdbe.org/6azs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6azs RCSB], [https://www.ebi.ac.uk/pdbsum/6azs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6azs ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BIUH_RHIJ3 BIUH_RHIJ3] Involved in the degradation of cyanuric acid, an intermediate in the degradation of s-triazide herbicides such as atrazine (PubMed:21897878). Catalyzes the hydrolysis of biuret to urea-1-carboxylate (allophanate) and ammonia (PubMed:21897878, PubMed:29425231). The substrate, biuret, is formed by the spontaneous decarboxylation of carboxybiuret (PubMed:21897878).<ref>PMID:21897878</ref> <ref>PMID:29425231</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Esquirol, L]]
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[[Category: Large Structures]]
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[[Category: Newman, J]]
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[[Category: Rhizobium leguminosarum bv. viciae 3841]]
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[[Category: Peat, T S]]
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[[Category: Esquirol L]]
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[[Category: Scott, C]]
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[[Category: Newman J]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Peat TS]]
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[[Category: S-triazine]]
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[[Category: Scott C]]
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[[Category: Xenobiotic]]
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Current revision

Structural and biochemical characterization of a non-canonical biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841

PDB ID 6azs

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