This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1q3a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:56, 16 August 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of the catalytic domain of human matrix metalloproteinase 10==
==Crystal structure of the catalytic domain of human matrix metalloproteinase 10==
-
<StructureSection load='1q3a' size='340' side='right' caption='[[1q3a]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='1q3a' size='340' side='right'caption='[[1q3a]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1q3a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q3A FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1q3a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q3A FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NGH:N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL+HYDROXAMIC+ACID'>NGH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g49|1g49]], [[1bqo|1bqo]], [[1d5j|1d5j]], [[1d8f|1d8f]], [[1uea|1uea]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NGH:N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL+HYDROXAMIC+ACID'>NGH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMP10 OR STMY2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q3a OCA], [https://pdbe.org/1q3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q3a RCSB], [https://www.ebi.ac.uk/pdbsum/1q3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q3a ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Stromelysin_2 Stromelysin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.22 3.4.24.22] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q3a OCA], [http://pdbe.org/1q3a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1q3a RCSB], [http://www.ebi.ac.uk/pdbsum/1q3a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1q3a ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/MMP10_HUMAN MMP10_HUMAN]] Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
+
[https://www.uniprot.org/uniprot/MMP10_HUMAN MMP10_HUMAN] Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 31: Line 29:
</div>
</div>
<div class="pdbe-citations 1q3a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1q3a" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Stromelysin 2]]
+
[[Category: Large Structures]]
-
[[Category: Bertini, I]]
+
[[Category: Bertini I]]
-
[[Category: Calderone, V]]
+
[[Category: Calderone V]]
-
[[Category: Fragai, M]]
+
[[Category: Fragai M]]
-
[[Category: Luchinat, C]]
+
[[Category: Luchinat C]]
-
[[Category: Mangani, S]]
+
[[Category: Mangani S]]
-
[[Category: Terni, B]]
+
[[Category: Terni B]]
-
[[Category: Hydrolase]]
+
-
[[Category: Hydroxamic acid]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Metalloproteinase]]
+
-
[[Category: Mmp-10]]
+
-
[[Category: Nngh]]
+
-
[[Category: Stromelysin-2]]
+

Current revision

Crystal structure of the catalytic domain of human matrix metalloproteinase 10

PDB ID 1q3a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1q3a"
Personal tools