1q6b

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{{Large structure}}
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==Solution Structure of the C-terminal Domain of Thermosynechococcus elongatus KaiA (ThKaiA180C); Ensemble of 25 Structures==
==Solution Structure of the C-terminal Domain of Thermosynechococcus elongatus KaiA (ThKaiA180C); Ensemble of 25 Structures==
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<StructureSection load='1q6b' size='340' side='right' caption='[[1q6b]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
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<StructureSection load='1q6b' size='340' side='right'caption='[[1q6b]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1q6b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theeb Theeb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q6B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1q6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermosynechococcus_vestitus_BP-1 Thermosynechococcus vestitus BP-1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q6B FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q6a|1q6a]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 25 models</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KaiA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=197221 THEEB])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q6b OCA], [https://pdbe.org/1q6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q6b RCSB], [https://www.ebi.ac.uk/pdbsum/1q6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q6b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q6b OCA], [http://pdbe.org/1q6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1q6b RCSB], [http://www.ebi.ac.uk/pdbsum/1q6b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1q6b ProSAT]</span></td></tr>
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</table>
</table>
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{{Large structure}}
 
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== Function ==
 
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[[http://www.uniprot.org/uniprot/KAIA_THEEB KAIA_THEEB]] Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q6/1q6b_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q6/1q6b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 1q6b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1q6b" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Circadian clock protein 3D structures|Circadian clock protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Theeb]]
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[[Category: Large Structures]]
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[[Category: Golden, S S]]
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[[Category: Thermosynechococcus vestitus BP-1]]
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[[Category: Holzenburg, A]]
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[[Category: Golden SS]]
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[[Category: LiWang, A C]]
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[[Category: Holzenburg A]]
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[[Category: Sun, J]]
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[[Category: LiWang AC]]
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[[Category: Vakonakis, I]]
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[[Category: Sun J]]
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[[Category: All alpha-helix protein]]
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[[Category: Vakonakis I]]
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[[Category: Circadian clock protein]]
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[[Category: Homodimer]]
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Current revision

Solution Structure of the C-terminal Domain of Thermosynechococcus elongatus KaiA (ThKaiA180C); Ensemble of 25 Structures

PDB ID 1q6b

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