2ev4

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[[Image:2ev4.gif|left|200px]]
 
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{{Structure
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==Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, with a salt precipitant==
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|PDB= 2ev4 |SIZE=350|CAPTION= <scene name='initialview01'>2ev4</scene>, resolution 2.28&Aring;
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<StructureSection load='2ev4' size='340' side='right'caption='[[2ev4]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>
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<table><tr><td colspan='2'>[[2ev4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EV4 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
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|GENE= Rv1264 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ev4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev4 OCA], [https://pdbe.org/2ev4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ev4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ev4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ev4 ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1y10|1Y10]], [[1y11|1Y11]], [[2ev1|2EV1]], [[2ev2|2EV2]], [[2ev3|2EV3]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ev4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev4 OCA], [http://www.ebi.ac.uk/pdbsum/2ev4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ev4 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Y1264_MYCTU Y1264_MYCTU] Catalyzes the formation of the second messenger cAMP.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/2ev4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ev4 ConSurf].
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<div style="clear:both"></div>
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'''Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, with a salt precipitant'''
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==See Also==
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*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2EV4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV4 OCA].
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[[Category: Large Structures]]
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[[Category: Adenylate cyclase]]
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
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[[Category: Findeisen F]]
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[[Category: Findeisen, F.]]
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[[Category: Sinning I]]
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[[Category: alpha-helical]]
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[[Category: Tews I]]
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[[Category: oleic acid]]
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[[Category: regulatory domain of adenylyl cyclase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:54:09 2008''
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Current revision

Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, with a salt precipitant

PDB ID 2ev4

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