2ev8

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[[Image:2ev8.gif|left|200px]]
 
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{{Structure
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==Solution structure of the erythroid p55 PDZ domain==
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|PDB= 2ev8 |SIZE=350|CAPTION= <scene name='initialview01'>2ev8</scene>
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<StructureSection load='2ev8' size='340' side='right'caption='[[2ev8]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2ev8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EV8 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ev8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev8 OCA], [https://pdbe.org/2ev8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ev8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ev8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ev8 ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ev8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev8 OCA], [http://www.ebi.ac.uk/pdbsum/2ev8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ev8 RCSB]</span>
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[https://www.uniprot.org/uniprot/EM55_HUMAN EM55_HUMAN] Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Solution structure of the erythroid p55 PDZ domain'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/2ev8_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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2EV8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV8 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ev8 ConSurf].
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Solution structure of human erythroid p55 PDZ domain., Kusunoki H, Kohno T, Proteins. 2006 Aug 15;64(3):804-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16741958 16741958]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kohno, T.]]
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[[Category: Kohno T]]
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[[Category: Kusunoki, H.]]
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[[Category: Kusunoki H]]
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[[Category: maguk]]
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[[Category: p55]]
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[[Category: pdz]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:54:13 2008''
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Current revision

Solution structure of the erythroid p55 PDZ domain

PDB ID 2ev8

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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