1psw

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==Structure of E. coli ADP-heptose lps heptosyltransferase II==
==Structure of E. coli ADP-heptose lps heptosyltransferase II==
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<StructureSection load='1psw' size='340' side='right' caption='[[1psw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1psw' size='340' side='right'caption='[[1psw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1psw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PSW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PSW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1psw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PSW FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rfaF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1psw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1psw OCA], [http://pdbe.org/1psw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1psw RCSB], [http://www.ebi.ac.uk/pdbsum/1psw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1psw ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/1psw TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1psw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1psw OCA], [https://pdbe.org/1psw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1psw RCSB], [https://www.ebi.ac.uk/pdbsum/1psw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1psw ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1psw TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/WAAF_ECOLI WAAF_ECOLI] Glycosyltransferase involved in the biosynthesis of the core oligosaccharide region of lipopolysaccharide (LPS) (PubMed:11054112). Catalyzes the addition of the second heptose unit to the heptosyl-Kdo2-lipid A module (PubMed:11054112, PubMed:11717579). The analog ADP-mannose can serve as an alternative donor in place of ADP-L-glycero-D-manno-heptose, but with lower efficiency (PubMed:11054112).<ref>PMID:11054112</ref> <ref>PMID:11717579</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/1psw_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/1psw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1psw ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1psw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Buglino, J]]
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[[Category: Large Structures]]
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[[Category: Burley, S K]]
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[[Category: Buglino J]]
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[[Category: Kniewel, R]]
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[[Category: Burley SK]]
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[[Category: Lima, C D]]
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[[Category: Kniewel R]]
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[[Category: Structural genomic]]
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[[Category: Lima CD]]
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[[Category: Solorzano, V]]
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[[Category: Solorzano V]]
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[[Category: Wu, J]]
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[[Category: Wu J]]
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[[Category: Lps biosynthetic pathway]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: T832]]
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[[Category: Transferase]]
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Current revision

Structure of E. coli ADP-heptose lps heptosyltransferase II

PDB ID 1psw

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OCA

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