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2f0l

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[[Image:2f0l.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of Staphylococcal nuclease mutant V23L/I72L==
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|PDB= 2f0l |SIZE=350|CAPTION= <scene name='initialview01'>2f0l</scene>, resolution 1.90&Aring;
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<StructureSection load='2f0l' size='340' side='right'caption='[[2f0l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2f0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0L FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0l OCA], [https://pdbe.org/2f0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0l RCSB], [https://www.ebi.ac.uk/pdbsum/2f0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0l ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[1ey0|1EY0]], [[2exz|2EXZ]], [[2ey1|2EY1]], [[2ey2|2EY2]], [[2ey5|2EY5]], [[2ey6|2EY6]], [[2eyf|2EYF]], [[2eyh|2EYH]], [[2eyj|2EYJ]], [[2eyl|2EYL]], [[2eym|2EYM]], [[2eyo|2EYO]], [[2eyp|2EYP]], [[2f0d|2F0D]], [[2f0e|2F0E]], [[2f0f|2F0F]], [[2f0g|2F0G]], [[2f0h|2F0H]], [[2f0i|2F0I]], [[2f0j|2F0J]], [[2f0k|2F0K]], [[2f0m|2F0M]], [[2f0n|2F0N]], [[2f0o|2F0O]], [[2f0p|2F0P]], [[2f0q|2F0Q]], [[2f0s|2F0S]], [[2f0t|2F0T]], [[2f0u|2F0U]], [[2f0v|2F0V]], [[2f0w|2F0W]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0l OCA], [http://www.ebi.ac.uk/pdbsum/2f0l PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2f0l RCSB]</span>
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[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0l ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of Staphylococcal nuclease mutant V23L/I72L'''
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==See Also==
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*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2F0L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0L OCA].
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[[Category: Large Structures]]
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[[Category: Micrococcal nuclease]]
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[[Category: Single protein]]
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[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Lu, J Z.]]
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[[Category: Lu JZ]]
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[[Category: Sakon, J.]]
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[[Category: Sakon J]]
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[[Category: Stites, W E.]]
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[[Category: Stites WE]]
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[[Category: calcium]]
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[[Category: dna hydrolase]]
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[[Category: endonuclease]]
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[[Category: rna hydrolase]]
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[[Category: signal]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:56:15 2008''
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Current revision

Crystal structure of Staphylococcal nuclease mutant V23L/I72L

PDB ID 2f0l

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