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5nhi

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==Crystal structure of the Escherichia coli N-terminal domain of DsbD (nDsbD) without the cap-loop region==
==Crystal structure of the Escherichia coli N-terminal domain of DsbD (nDsbD) without the cap-loop region==
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<StructureSection load='5nhi' size='340' side='right' caption='[[5nhi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='5nhi' size='340' side='right'caption='[[5nhi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5nhi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NHI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5nhi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NHI FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhi OCA], [http://pdbe.org/5nhi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nhi RCSB], [http://www.ebi.ac.uk/pdbsum/5nhi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhi ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhi OCA], [https://pdbe.org/5nhi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nhi RCSB], [https://www.ebi.ac.uk/pdbsum/5nhi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0A0GNS2_ECOLX A0A0A0GNS2_ECOLX]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.[HAMAP-Rule:MF_00399]
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[https://www.uniprot.org/uniprot/DSBD_ECOLI DSBD_ECOLI] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of DsbC, DsbE and DsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.[HAMAP-Rule:MF_00399]
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==See Also==
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*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Protein-disulfide reductase]]
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[[Category: Escherichia coli]]
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[[Category: Mavridou, D A.I]]
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[[Category: Large Structures]]
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[[Category: Redfield, C]]
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[[Category: Mavridou DAI]]
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[[Category: Saridakis, E]]
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[[Category: Redfield C]]
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[[Category: Stelzl, L S]]
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[[Category: Saridakis E]]
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[[Category: Electron transport]]
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[[Category: Stelzl LS]]
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[[Category: Immunoglobulin-like fold]]
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[[Category: Oxidoreductase]]
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[[Category: Thiol disulfide oxidoreductase]]
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Current revision

Crystal structure of the Escherichia coli N-terminal domain of DsbD (nDsbD) without the cap-loop region

PDB ID 5nhi

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