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2f65

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[[Image:2f65.gif|left|200px]]
 
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{{Structure
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==Solution structure of HPPK in complex with inhibitor analog AMPCPP==
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|PDB= 2f65 |SIZE=350|CAPTION= <scene name='initialview01'>2f65</scene>
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<StructureSection load='2f65' size='340' side='right'caption='[[2f65]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2f65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F65 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= folK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f65 OCA], [https://pdbe.org/2f65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f65 RCSB], [https://www.ebi.ac.uk/pdbsum/2f65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f65 ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[1eq0|1EQ0]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f65 OCA], [http://www.ebi.ac.uk/pdbsum/2f65 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2f65 RCSB]</span>
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[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/2f65_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f65 ConSurf].
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<div style="clear:both"></div>
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'''Solution structure of HPPK in complex with inhibitor analog AMPCPP'''
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==See Also==
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*[[HPPK 3D structures|HPPK 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2F65 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F65 OCA].
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Li, G.]]
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[[Category: Li G]]
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[[Category: Yan, H.]]
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[[Category: Yan H]]
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[[Category: alpha-beta-alpha fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:58:26 2008''
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Current revision

Solution structure of HPPK in complex with inhibitor analog AMPCPP

PDB ID 2f65

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