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5ovc

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==PDZ domain from rat Shank3 bound to the C terminus of GKAP==
==PDZ domain from rat Shank3 bound to the C terminus of GKAP==
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<StructureSection load='5ovc' size='340' side='right' caption='[[5ovc]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='5ovc' size='340' side='right'caption='[[5ovc]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ovc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OVC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ovc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OVC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ovc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ovc OCA], [http://pdbe.org/5ovc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ovc RCSB], [http://www.ebi.ac.uk/pdbsum/5ovc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ovc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ovc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ovc OCA], [https://pdbe.org/5ovc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ovc RCSB], [https://www.ebi.ac.uk/pdbsum/5ovc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ovc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SHAN3_RAT SHAN3_RAT]] Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
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[https://www.uniprot.org/uniprot/SHAN3_RAT SHAN3_RAT] Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ovc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ovc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Shank protein|Shank protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Boeckers, T M]]
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[[Category: Large Structures]]
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[[Category: Kursula, P]]
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[[Category: Rattus norvegicus]]
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[[Category: Myllykoski, M]]
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[[Category: Boeckers TM]]
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[[Category: Ponna, S K]]
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[[Category: Kursula P]]
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[[Category: C terminus]]
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[[Category: Myllykoski M]]
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[[Category: Pdz domain]]
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[[Category: Ponna SK]]
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[[Category: Peptide binding]]
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[[Category: Post-synaptic density]]
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[[Category: Protein binding]]
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Current revision

PDZ domain from rat Shank3 bound to the C terminus of GKAP

PDB ID 5ovc

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