5v12

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:28, 1 May 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
==Carbon Sulfoxide lyase, Egt2 in the Ergothioneine biosynthesis pathway==
+
==Crystal structure of Carbon Sulfoxide lyase, Egt2 Y134F with sulfenic acid intermediate==
-
<StructureSection load='5v12' size='340' side='right' caption='[[5v12]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
+
<StructureSection load='5v12' size='340' side='right'caption='[[5v12]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5v12]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V12 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V12 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5v12]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Neurospora_crassa_OR74A Neurospora crassa OR74A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V12 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8QJ:(2~{S})-3-(2-oxidanylsulfanyl-1~{H}-imidazol-4-yl)-2-(trimethyl-$l^{4}-azanyl)propanoic+acid'>8QJ</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.451&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=EXA:'>EXA</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8QJ:(2~{S})-3-(2-oxidanylsulfanyl-1~{H}-imidazol-4-yl)-2-(trimethyl-$l^{4}-azanyl)propanoic+acid'>8QJ</scene>, <scene name='pdbligand=EXA:N~6~-[(R)-[(E)-(1-carboxyethylidene)amino]{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl]-L-lysine'>EXA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v12 OCA], [http://pdbe.org/5v12 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v12 RCSB], [http://www.ebi.ac.uk/pdbsum/5v12 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v12 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v12 OCA], [https://pdbe.org/5v12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v12 RCSB], [https://www.ebi.ac.uk/pdbsum/5v12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v12 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/EGT2_NEUCR EGT2_NEUCR]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Irani, S]]
+
[[Category: Large Structures]]
-
[[Category: Zhang, Y]]
+
[[Category: Neurospora crassa OR74A]]
-
[[Category: C-s lyase]]
+
[[Category: Irani S]]
-
[[Category: Lyase]]
+
[[Category: Zhang Y]]
-
[[Category: Plp dependent]]
+

Current revision

Crystal structure of Carbon Sulfoxide lyase, Egt2 Y134F with sulfenic acid intermediate

PDB ID 5v12

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools