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4j0n

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==Crystal structure of a manganese dependent isatin hydrolase==
==Crystal structure of a manganese dependent isatin hydrolase==
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<StructureSection load='4j0n' size='340' side='right' caption='[[4j0n]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='4j0n' size='340' side='right'caption='[[4j0n]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j0n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Labai Labai]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J0N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j0n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Roseibium_aggregatum_IAM_12614 Roseibium aggregatum IAM 12614]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J0N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIAM614_09648 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=384765 LABAI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j0n OCA], [http://pdbe.org/4j0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j0n RCSB], [http://www.ebi.ac.uk/pdbsum/4j0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j0n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j0n OCA], [https://pdbe.org/4j0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j0n RCSB], [https://www.ebi.ac.uk/pdbsum/4j0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j0n ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ISAHY_ROSAI ISAHY_ROSAI] Involved in the degradation of the plant hormone indole-3-acetic acid (IAA). Catalyzes the hydrolysis of the cyclic amide bond (lactam) of isatin (1H-indole-2,3-dione) to yield isatinate (2-(2-aminophenyl)-2-oxoacetate).<ref>PMID:24917679</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Labai]]
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[[Category: Large Structures]]
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[[Category: Bjerregaard-Andersen, K]]
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[[Category: Roseibium aggregatum IAM 12614]]
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[[Category: Etzerodt, M]]
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[[Category: Bjerregaard-Andersen K]]
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[[Category: Jensen, J K]]
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[[Category: Etzerodt M]]
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[[Category: Jochimsen, B]]
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[[Category: Jensen JK]]
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[[Category: Morth, J P]]
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[[Category: Jochimsen B]]
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[[Category: Sommer, T]]
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[[Category: Morth JP]]
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[[Category: Hydrolase]]
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[[Category: Sommer T]]
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[[Category: Manganese binding]]
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Current revision

Crystal structure of a manganese dependent isatin hydrolase

PDB ID 4j0n

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