1s0j

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==Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)==
==Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)==
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<StructureSection load='1s0j' size='340' side='right' caption='[[1s0j]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='1s0j' size='340' side='right'caption='[[1s0j]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1s0j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S0J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1s0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S0J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MUS:4-METHYL-2-OXO-2H-CHROMEN-7-YL+5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC+ACID'>MUS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s0i|1s0i]], [[1s0k|1s0k]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MUS:4-METHYL-2-OXO-2H-CHROMEN-7-YL+5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC+ACID'>MUS</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s0j OCA], [https://pdbe.org/1s0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s0j RCSB], [https://www.ebi.ac.uk/pdbsum/1s0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s0j ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s0j OCA], [http://pdbe.org/1s0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s0j RCSB], [http://www.ebi.ac.uk/pdbsum/1s0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1s0j ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q26966_TRYCR Q26966_TRYCR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s0/1s0j_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s0/1s0j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Exo-alpha-sialidase]]
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[[Category: Large Structures]]
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[[Category: Trycr]]
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[[Category: Alzari, P M]]
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[[Category: Amaya, M F]]
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[[Category: Buschiazzo, A]]
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[[Category: Damager, I]]
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[[Category: Frasch, A C]]
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[[Category: Nguyen, T]]
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[[Category: Paris, G]]
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[[Category: Watts, A G]]
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[[Category: Wehenkel, A]]
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[[Category: Withers, S G]]
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[[Category: Hydrolase]]
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[[Category: Michaelis complex]]
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[[Category: Transglycosidase]]
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[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Alzari PM]]
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[[Category: Amaya MF]]
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[[Category: Buschiazzo A]]
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[[Category: Damager I]]
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[[Category: Frasch AC]]
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[[Category: Nguyen T]]
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[[Category: Paris G]]
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[[Category: Watts AG]]
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[[Category: Wehenkel A]]
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[[Category: Withers SG]]

Current revision

Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)

PDB ID 1s0j

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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