User:Mark Macbeth/Sandbox1
From Proteopedia
< User:Mark Macbeth(Difference between revisions)
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| - | + | ='''RNA Lariat Debranching Enzyme with Zn and Mn'''= | |
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| - | <StructureSection load=' | + | |
| - | + | <StructureSection load='DbrRNA.pdb' size='340' frame='true' side='right' caption='Zn-Mn phosphodiesterase' scene='78/782584/Loadscenetest/1'> | |
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| + | ==Introduction== | ||
| + | [[Image:dbr1.png|300 px|left|thumb|Figure 1: The Zn and Mn binding sites of Dbr1]] | ||
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| + | <scene name='78/782584/Metal_coordination_1/3'>TextToBeDisplayed</scene> | ||
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| + | ==Structure== | ||
| + | There will be some interesting text here soon! For now, enjoy this soothing whitespace below..... | ||
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| + | <scene name='87/877553/His415_white/1'>His415</scene> | ||
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| + | ==Structural highlights== | ||
| + | This protein is absolutely amazing. If you keep reading you will be astounded by its sheer amazingness. I can't wait to tell you all about it. But you will have to wait until I have more time. Or until we get scooped again. <scene name='78/782584/Test1/5'>Here is a cool part of this protein (not really)!!</scene> | ||
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| + | This is to show a dash line connecting the Zn and a Cys residue: <scene name='78/782584/Cys_zn/3'>cys-Zn</scene> | ||
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| + | And finally - this link was made to load the initial scene on the page. <scene name='78/782584/Loadscenetest/1'>Loadscenetest</scene> | ||
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| + | <scene name='78/782584/Metal_coordination/1'>TextToBeDisplayed</scene> | ||
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| + | The awesome CH462 students are much better at this than I am. I am very proud of their work.<ref name="Shibuya"> PMID:26669800</ref><ref name="Ransey"> PMID:28504306</ref> | ||
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| + | </StructureSection> | ||
== Function == | == Function == | ||
===RNA Debranching=== | ===RNA Debranching=== | ||
| - | <scene name='78/782584/Test1/5'>Here is a cool part of this protein!!</scene> | ||
| - | == Disease == | ||
| - | == | + | ===Disease=== |
| - | == | + | ===Relevance=== |
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| + | <scene name='78/782584/Metal_coordination_1/1'>TextToBeDisplayed</scene> | ||
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| + | <scene name='78/782584/Metal_coordination_1/4'>scene transition</scene> | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
| - | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
Contents |
RNA Lariat Debranching Enzyme with Zn and Mn
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Function
RNA Debranching
Disease
Relevance
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Shibuya Y, Chang CC, Chang TY. ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease. Future Med Chem. 2015;7(18):2451-67. doi: 10.4155/fmc.15.161. Epub 2015 Dec 15. PMID:26669800 doi:http://dx.doi.org/10.4155/fmc.15.161
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
