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2frv

From Proteopedia

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[[Image:2frv.gif|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF NI-FE HYDROGENASE==
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|PDB= 2frv |SIZE=350|CAPTION= <scene name='initialview01'>2frv</scene>, resolution 2.54&Aring;
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<StructureSection load='2frv' size='340' side='right'caption='[[2frv]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
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|SITE= <scene name='pdbsite=ACT:Ni-Fe+Active+Site'>ACT</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FCO:CARBONMONOXIDE-(DICYANO)+IRON'>FCO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>
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<table><tr><td colspan='2'>[[2frv]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Megalodesulfovibrio_gigas Megalodesulfovibrio gigas]. The March 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Hydrogenase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_3 10.2210/rcsb_pdb/mom_2009_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FRV FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin_hydrogenase Ferredoxin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.7.2 1.12.7.2] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FCO:CARBONMONOXIDE-(DICYANO)+IRON'>FCO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2frv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2frv OCA], [https://pdbe.org/2frv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2frv RCSB], [https://www.ebi.ac.uk/pdbsum/2frv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2frv ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2frv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2frv OCA], [http://www.ebi.ac.uk/pdbsum/2frv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2frv RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PHNS_MEGGA PHNS_MEGGA]
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== Evolutionary Conservation ==
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'''CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF NI-FE HYDROGENASE'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/2frv_consurf.spt"</scriptWhenChecked>
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2FRV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRV OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Desulfovibrio gigas]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Ferredoxin hydrogenase]]
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</jmolCheckbox>
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[[Category: Protein complex]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2frv ConSurf].
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[[Category: Fontecilla-Camps, J C.]]
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<div style="clear:both"></div>
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[[Category: Frey, M.]]
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__TOC__
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[[Category: Volbeda, A.]]
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</StructureSection>
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[[Category: ni-fe hydrogenase]]
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[[Category: Hydrogenase]]
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[[Category: oxidoreductase]]
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[[Category: Large Structures]]
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[[Category: Megalodesulfovibrio gigas]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:06:52 2008''
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Fontecilla-Camps JC]]
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[[Category: Frey M]]
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[[Category: Volbeda A]]

Current revision

CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF NI-FE HYDROGENASE

PDB ID 2frv

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