2ftp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:31, 30 August 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2ftp.gif|left|200px]]
 
-
{{Structure
+
==Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa==
-
|PDB= 2ftp |SIZE=350|CAPTION= <scene name='initialview01'>2ftp</scene>, resolution 2.40&Aring;
+
<StructureSection load='2ftp' size='340' side='right'caption='[[2ftp]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
+
<table><tr><td colspan='2'>[[2ftp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FTP FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_lyase Hydroxymethylglutaryl-CoA lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.4 4.1.3.4] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK05692 PRK05692]</span>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ftp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ftp OCA], [https://pdbe.org/2ftp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ftp RCSB], [https://www.ebi.ac.uk/pdbsum/2ftp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ftp ProSAT], [https://www.topsan.org/Proteins/MCSG/2ftp TOPSAN]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ftp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ftp OCA], [http://www.ebi.ac.uk/pdbsum/2ftp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ftp RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/LIUE_PSEAE LIUE_PSEAE] Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate.<ref>PMID:19459965</ref> <ref>PMID:19597963</ref>
-
 
+
== Evolutionary Conservation ==
-
'''Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa'''
+
[[Image:Consurf_key_small.gif|200px|right]]
-
 
+
Check<jmol>
-
 
+
<jmolCheckbox>
-
==About this Structure==
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/2ftp_consurf.spt"</scriptWhenChecked>
-
2FTP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTP OCA].
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Hydroxymethylglutaryl-CoA lyase]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Pseudomonas aeruginosa pao1]]
+
</jmolCheckbox>
-
[[Category: Single protein]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ftp ConSurf].
-
[[Category: Edwards, A.]]
+
<div style="clear:both"></div>
-
[[Category: Evdokimova, E.]]
+
== References ==
-
[[Category: Kudritska, M.]]
+
<references/>
-
[[Category: Liu, Y.]]
+
__TOC__
-
[[Category: MCSG, Midwest Center for Structural Genomics.]]
+
</StructureSection>
-
[[Category: Pai, E F.]]
+
[[Category: Large Structures]]
-
[[Category: Savchenko, A.]]
+
[[Category: Pseudomonas aeruginosa PAO1]]
-
[[Category: Xiao, T.]]
+
[[Category: Edwards A]]
-
[[Category: lyase]]
+
[[Category: Evdokimova E]]
-
[[Category: mcsg]]
+
[[Category: Kudritska M]]
-
[[Category: midwest center for structural genomic]]
+
[[Category: Liu Y]]
-
[[Category: protein structure initiative]]
+
[[Category: Pai EF]]
-
[[Category: psi]]
+
[[Category: Savchenko A]]
-
[[Category: structural genomic]]
+
[[Category: Xiao T]]
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:07:30 2008''
+

Current revision

Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa

PDB ID 2ftp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ftp"
Personal tools