1txl

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==Crystal structure of metal-binding protein yodA from E. coli, Pfam DUF149==
==Crystal structure of metal-binding protein yodA from E. coli, Pfam DUF149==
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<StructureSection load='1txl' size='340' side='right' caption='[[1txl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1txl' size='340' side='right'caption='[[1txl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1txl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TXL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1txl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TXL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YODA, B1973 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1txl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1txl OCA], [http://pdbe.org/1txl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1txl RCSB], [http://www.ebi.ac.uk/pdbsum/1txl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1txl ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/1txl TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1txl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1txl OCA], [https://pdbe.org/1txl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1txl RCSB], [https://www.ebi.ac.uk/pdbsum/1txl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1txl ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1txl TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ZINT_ECOLI ZINT_ECOLI]] May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites.<ref>PMID:17931600</ref> <ref>PMID:19377097</ref>
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[https://www.uniprot.org/uniprot/ZINT_ECOLI ZINT_ECOLI] May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites.<ref>PMID:17931600</ref> <ref>PMID:19377097</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tx/1txl_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tx/1txl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Burley, S K]]
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[[Category: Large Structures]]
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[[Category: Eswaramoorthy, S]]
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[[Category: Burley SK]]
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[[Category: Structural genomic]]
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[[Category: Eswaramoorthy S]]
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[[Category: Swaminathan, S]]
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[[Category: Swaminathan S]]
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[[Category: E coli]]
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[[Category: New fold]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Unknown function]]
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[[Category: Yoda]]
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Current revision

Crystal structure of metal-binding protein yodA from E. coli, Pfam DUF149

PDB ID 1txl

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