5zj3

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m (Protected "5zj3" [edit=sysop:move=sysop])
Current revision (06:48, 3 April 2019) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5zj3 is ON HOLD
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==Textilinin-1, A Kunitz-Type Serine Protease Inhibitor From pichia expression system==
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<StructureSection load='5zj3' size='340' side='right'caption='[[5zj3]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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Authors: Ou, X.J., li, N.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zj3]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZJ3 FirstGlance]. <br>
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Description: Textilinin-1, A Kunitz-Type Serine Protease Inhibitor From pichia expression system
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zj3 OCA], [http://pdbe.org/5zj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zj3 RCSB], [http://www.ebi.ac.uk/pdbsum/5zj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zj3 ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Ou, X.J]]
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== Function ==
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[[http://www.uniprot.org/uniprot/VKT1_PSETT VKT1_PSETT]] Strongly inhibits plasmin (Ki=0.44 nM) and trypsin (Ki=0.42 nM). Has little effect on plasma (Ki=1870 nM) and tissue (Ki=12900 nM) kallikreins. In vivo, reduces bleeding in a small animal model.<ref>PMID:10847427</ref> <ref>PMID:12406072</ref> <ref>PMID:16707925</ref> <ref>PMID:19236611</ref> <ref>PMID:21843588</ref> <ref>PMID:23335990</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Ou, X J]]
[[Category: Li, N]]
[[Category: Li, N]]
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[[Category: A kunitz-type serine protease inhibitor from]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Textilinin-1]]

Current revision

Textilinin-1, A Kunitz-Type Serine Protease Inhibitor From pichia expression system

PDB ID 5zj3

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