6cnh
From Proteopedia
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==Human PRPF4B in complex with Rebastinib== | ==Human PRPF4B in complex with Rebastinib== | ||
| - | <StructureSection load='6cnh' size='340' side='right' caption='[[6cnh]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='6cnh' size='340' side='right'caption='[[6cnh]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CNH FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [https://pdbe.org/6cnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [https://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arruda | + | [[Category: Large Structures]] |
| - | [[Category: Counago | + | [[Category: Arruda P]] |
| - | [[Category: Edwards | + | [[Category: Counago RM]] |
| - | [[Category: Elkins | + | [[Category: Edwards AM]] |
| - | [[Category: Fala | + | [[Category: Elkins JM]] |
| - | [[Category: Gileadi | + | [[Category: Fala AM]] |
| - | [[Category: Godoi | + | [[Category: Gileadi O]] |
| - | [[Category: Guimaraes | + | [[Category: Godoi PHC]] |
| - | [[Category: Massirer | + | [[Category: Guimaraes CRW]] |
| - | [[Category: Ramos | + | [[Category: Massirer KB]] |
| - | [[Category: Righetto | + | [[Category: Ramos PZ]] |
| - | + | [[Category: Righetto GL]] | |
| - | [[Category: Salmazo | + | [[Category: Salmazo APT]] |
| - | [[Category: Santiago | + | [[Category: Santiago AS]] |
| - | [[Category: Silva | + | [[Category: Silva PNB]] |
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Current revision
Human PRPF4B in complex with Rebastinib
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Categories: Homo sapiens | Large Structures | Arruda P | Counago RM | Edwards AM | Elkins JM | Fala AM | Gileadi O | Godoi PHC | Guimaraes CRW | Massirer KB | Ramos PZ | Righetto GL | Salmazo APT | Santiago AS | Silva PNB
