This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1uh1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:36, 25 October 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of jacalin- GalNAc-beta(1-3)-Gal-alpha-O-Me complex==
==Crystal structure of jacalin- GalNAc-beta(1-3)-Gal-alpha-O-Me complex==
-
<StructureSection load='1uh1' size='340' side='right' caption='[[1uh1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+
<StructureSection load='1uh1' size='340' side='right'caption='[[1uh1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1uh1]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UH1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1uh1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UH1 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMG:ALPHA-METHYL-D-GALACTOSIDE'>AMG</scene>, <scene name='pdbligand=MGC:ALPHA-METHYL-N-ACETYL-D-GALACTOSAMINE'>MGC</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m26|1m26]], [[1jac|1jac]], [[1ugw|1ugw]], [[1ugx|1ugx]], [[1ugy|1ugy]], [[1uh0|1uh0]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMG:ALPHA-METHYL-D-GALACTOSIDE'>AMG</scene>, <scene name='pdbligand=MGC:ALPHA-METHYL-N-ACETYL-D-GALACTOSAMINE'>MGC</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uh1 OCA], [http://pdbe.org/1uh1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uh1 RCSB], [http://www.ebi.ac.uk/pdbsum/1uh1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uh1 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uh1 OCA], [https://pdbe.org/1uh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uh1 RCSB], [https://www.ebi.ac.uk/pdbsum/1uh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uh1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. [[http://www.uniprot.org/uniprot/LECB3_ARTIN LECB3_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
+
[https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 31: Line 31:
==See Also==
==See Also==
-
*[[Agglutinin|Agglutinin]]
+
*[[Agglutinin 3D structures|Agglutinin 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 37: Line 37:
</StructureSection>
</StructureSection>
[[Category: Artocarpus integer]]
[[Category: Artocarpus integer]]
-
[[Category: Jeyaprakash, A A]]
+
[[Category: Large Structures]]
-
[[Category: Katiyar, S]]
+
[[Category: Jeyaprakash AA]]
-
[[Category: Sekar, K]]
+
[[Category: Katiyar S]]
-
[[Category: Surolia, A]]
+
[[Category: Sekar K]]
-
[[Category: Swaminathan, C P]]
+
[[Category: Surolia A]]
-
[[Category: Vijayan, M]]
+
[[Category: Swaminathan CP]]
-
[[Category: All beta sheet protein]]
+
[[Category: Vijayan M]]
-
[[Category: Beta-prism i fold]]
+
-
[[Category: Gal specific]]
+
-
[[Category: Sugar binding protein]]
+

Current revision

Crystal structure of jacalin- GalNAc-beta(1-3)-Gal-alpha-O-Me complex

PDB ID 1uh1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1uh1"
Personal tools