Basic Pancreatic Trypsin Inhibitor
From Proteopedia
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<scene name='43/430026/Cv/3'>Residue K15 of BPTI</scene> extends into the active site of trypsin and inhibits its proteolytic function. <ref>PMID:10210204</ref> | <scene name='43/430026/Cv/3'>Residue K15 of BPTI</scene> extends into the active site of trypsin and inhibits its proteolytic function. <ref>PMID:10210204</ref> | ||
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| - | </StructureSection> | ||
== 3D Structures of BPTI == | == 3D Structures of BPTI == | ||
| + | [[BPTI 3D structures]] | ||
| - | + | </StructureSection> | |
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| - | **[[3fp6]] – rBPTI+anionic trypsin – rat<br /> | ||
| - | **[[3tgi]], [[1bzx]] - bBPTI+anionic trypsin<br /> | ||
| - | **[[2ptc]] – bBPTI + β-trypsin<br /> | ||
| - | **[[1co7]], [[1f5r]], [[1f7z]], [[3tgk]] - rBPTI+anionic trypsin (mutant)<br /> | ||
| - | **[[3tgj]] - bBPTI+anionic trypsin (mutant)<br /> | ||
| - | **[[3fp7]], [[3fp8]], [[1fy8]] – rBPTI (mutant) +anionic trypsin<br /> | ||
| - | **[[2r9p]] – bBPTI+hMesotrypsin (mutant)<br /> | ||
| - | **[[3p92]], [[3p95]] – bBPTI (mutant) +hMesotrypsin (mutant)<br /> | ||
| - | **[[1tpa]] - bBPTI+hAnhydro-trypsin<br /> | ||
| - | **[[2ra3]] - bBPTI+hTrypsin cationic (mutant)<br /> | ||
| - | **[[2ijo]] – bBPTI+West Nile virus protease<br /> | ||
| - | **[[3u1j]] - bBPTI+ Dengue virus protease<br /> | ||
| - | **[[1ykt]] – bBPTI+rTrypsin II (mutant)<br /> | ||
| - | **[[1ylc]], [[1yld]] - bBPTI (mutant)+ rTrypsin II (mutant)<br /> | ||
| - | **[[2ftl]], [[3btk]], [[4y0y]] - bBPTI+bTrypsin cationic <br /> | ||
| - | **[[1brb]], [[3otj]] - bBPTI+rTrypsin cationic<br /> | ||
| - | **[[4wwy]], [[4wxv]] - bBPTI+ hTrypsin cationic – human<br /> | ||
| - | **[[2ftm]], [[2fi3]], [[2fi5]], [[1ejm]], [[4y0z]], [[4y10]], [[4y11]] – bBPTI (mutant)+bTrypsin cationic<br /> | ||
| - | **[[3bte]], [[3btq]], [[3btd]], [[3btf]], [[3btg]], [[3bth]], [[3btm]], [[3btt]], [[3btw]], [[1aal]], [[6pti]] - bBPTI (mutant)+bTrypsin<br /> | ||
| - | **[[2fi4]] - bBPTI (mutant)+bTrypsin cationic (mutant)<br /> | ||
| - | **[[1t7c]], [[1t8l]] - bBPTI (mutant)+bChymotrypsin <br /> | ||
| - | **[[1cbw]], [[1mtn]] - bBPTI+bChymotrypsin A<br /> | ||
| - | **[[1t8m]], [[1t8n]], [[1t8o]] - bBPTI +bChymotrypsin A (mutant)<br /> | ||
| - | **[[1p2i]], [[1p2j]], [[1p2k]] - bBPTI (mutant)+bTrypsinogen<br /> | ||
| - | **[[3tpi]], [[4tpi]], [[2tgp]], [[2tpi]] - bBPTI + bTrypsinogen<br /> | ||
| - | **[[1p2m]], [[1p2n]], [[1p2o]], [[1p2q]] - bBPTI (mutant)+bChymotrypsinogen A<br /> | ||
| - | **[[1eaw]] – bBPTI+hMatriptase<br /> | ||
| - | **[[1d0d]] – bBPTI+anticoagulant protein – tick<br /> | ||
| - | **[[2kai]] – bBPTI + kallikrein A<br /> | ||
| - | **[[3gym]] – bBPTI + prostasin<br /> | ||
| - | **[[4dg4]] – bBPTI + PRSS3 protein (mutant)<br /> | ||
| - | **[[4bnr]] - bBPTI+ hepatopancreas trypsin<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
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References
- ↑ Parkin S, Rupp B, Hope H. Structure of bovine pancreatic trypsin inhibitor at 125 K definition of carboxyl-terminal residues Gly57 and Ala58. Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):18-29. PMID:15299722 doi:http://dx.doi.org/10.1107/S0907444995008675
- ↑ Pasternak A, Ringe D, Hedstrom L. Comparison of anionic and cationic trypsinogens: the anionic activation domain is more flexible in solution and differs in its mode of BPTI binding in the crystal structure. Protein Sci. 1999 Jan;8(1):253-8. PMID:10210204
