1ufv

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==Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8==
==Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8==
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<StructureSection load='1ufv' size='340' side='right' caption='[[1ufv]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='1ufv' size='340' side='right'caption='[[1ufv]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ufv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UFV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ufv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UFV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PanC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ufv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufv OCA], [https://pdbe.org/1ufv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ufv RCSB], [https://www.ebi.ac.uk/pdbsum/1ufv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufv ProSAT], [https://www.topsan.org/Proteins/RSGI/1ufv TOPSAN]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ufv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufv OCA], [http://pdbe.org/1ufv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ufv RCSB], [http://www.ebi.ac.uk/pdbsum/1ufv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufv ProSAT], [http://www.topsan.org/Proteins/RSGI/1ufv TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PANC_THET8 PANC_THET8]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).[HAMAP-Rule:MF_00158]
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[https://www.uniprot.org/uniprot/PANC_THET8 PANC_THET8] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).[HAMAP-Rule:MF_00158]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufv_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
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[[Category: Large Structures]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Thermus thermophilus]]
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[[Category: Bagautdinov, B]]
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[[Category: Bagautdinov B]]
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[[Category: Kuramitsu, S]]
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[[Category: Kuramitsu S]]
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[[Category: Miyano, M]]
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[[Category: Miyano M]]
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[[Category: Structural genomic]]
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[[Category: Tahirov TH]]
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[[Category: Tahirov, T H]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Dimer]]
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[[Category: Domain]]
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[[Category: Ligase]]
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[[Category: Rossmann fold]]
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[[Category: Rsgi]]
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Current revision

Crystal Structure Of Pantothenate Synthetase From Thermus Thermophilus HB8

PDB ID 1ufv

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